PIPELINE
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Stem Cell Therapy
Moderate to severe atopic dermatitis
01
Disease Overview
It is a chronic, recurrent inflammatory skin disease that begins in infancy or childhood.
Accompanied by pruritus, dry skin, characteristic eczema, and lichenification.
Definition
- Atopic dermatitis is a chronic recurrent inflammatory skin disease that mainly begins in infancy or childhood, and is accompanied by pruritus (itch), dry skin, and characteristic eczema.
Cause
- The cause of the disease is still unknown.
- Environmental factors, genetic predisposition, immunological abnormalities, and abnormal skin barrier are the main causes.
Symptom
- Severe itching (itching), dry skin, and dermatitis (eczema) are the main symptoms.
- Dry skin causes and exacerbates itching, which is intermittent during the day and usually gets worse in the early evening or in the middle of the night.
02
Phase 2 clinical design
Primary endpoint : The percentage of subjects who have EASI-50 at Week 12.
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Indicationmoderate to severe
atopic dermatitis
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Number of subjects72 people
Cohort 1: 36 subjects in the test group
Cohort 2: 36 subjects in the placebo group -
Dosing regimen2 weeks intervals / 3 times
0.5 X 106 cells/kg
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Designmulticenter, placebo-controlled, double-blind
clinical trial institution
