- Atopic dermatitis is a chronic recurrent inflammatory skin disease that mainly begins in infancy or childhood, and is accompanied by pruritus (itch), dry skin, and characteristic eczema.
- The cause of the disease is still unknown
- Environmental factors, genetic predisposition, immunological abnormalities, and abnormal skin barrier are the main causes.
- Severe itching (itching), dry skin, and dermatitis (eczema) are the main symptoms
- Dry skin causes and exacerbates itching, which is intermittent during the day and usually gets worse in the early evening or in the middle of the night.
Primary endpoint : rate of change of EASI score at 12 weeks (EASI-50)
(Eczema Area and Severity Index , Eczema Severity Index)
Indicationmoderate to severe
Number of patients72 people
Cohort 1: 36 subjects in the test group
Cohort 2: 36 patients in the placebo group
Dosing regimen2 weeks intervals / 3 times
0.5 X 106 cells/kg
Designmulticenter, placebo-controlled, double-blind